نوع مقاله : مقاله پژوهشی
نویسندگان
1 عضو هیئت علمی دانشگاه آزاد اسلامی واحد تهران جنوب
2 تهران،دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه مهندسی نساجی
3 تهران،دانشگاه آزاد اسلامی، واحد علوم و تحقیقات، گروه مهندسی نساجی،کدپستی۱۴۷۷۸۹۳۸۵۵
4 تهران - دانشگاه آزاد اسلامی، واحد علوم پزشکی ایران، گروه میکروب شناسی،کدپستی۱۹۱۶۸۹۳۸۱۳
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Advanced wound dresses are antimicrobial materials that can keep the wound surroundings moist and do not stick to wound. Therefore, in this research, the purpose is to coat a antimicrobial nanoemulsion on a polypropylene(PP) substrate to achieve the mentioned characteristics. non-woven samples of PP were coated with nanoemulsion (2g lipid, 0.3g carboxymethyl cellulose, 10 ml nanosilver) and drug containing nano emulsion (0.25g mupirocin, 0.25g lidocaine and 0.025g betamethasone). The specimens were characterized by infrared spectroscopy (FTIR), scanning electron microscopy to examine morphological structure, projectina microscopy, antimicrobial tests, water absorption and water maintenance teste. Scanning electron microscopy and projector microscopy and FTIR spectroscopy results confirmed the subsidence of nanoemulsion (EL-CS) and drug containing nano emulsion in the PP substrate, both coated samples ( EL-CS and EL-CS+MLB) completely inhibited growth of both gram-negative (E-Coli) and positive ( S-Areus) bacterias. The results of water absorption and water maintenance experiments showed that EL-CS coated samples had more absorbtion time (30 min) and water storage (60 min) comparing to non wrapped samples, but the EL-CS+MLB specimen did not show a significant difference in the two above-mentioned factors comparing to EL-CS. the prepared nanoemulsions and wound dresses obtained from them can have acceptable properties from use in medical appliations
کلیدواژه‌ها [English]
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