This study aimed to investigate the role of cultural, social, and media factors in shaping the sustainable fashion design mindset among clothing design students at Islamic Azad University, Tehran South Branch. The present research is applied in terms of purpose and descriptive-correlational in terms of method. The statistical population consisted of clothing design students, from whom 384 participants were selected using random sampling. Data were collected through a questionnaire, and the validity of the instrument was confirmed by experts’ opinions, while its reliability was verified using Cronbach’s alpha coefficient of 0.94. To examine the structure of variables and the relationships among them, exploratory factor analysis and multiple regression analysis were performed using SPSS27 software. The findings indicated that the KMO index was 0.82, and the three extracted factors explained 72% of the total variance. The results of multiple regression analysis showed that cultural factors had the highest predictive power for the sustainable fashion design mindset, with a standardized beta coefficient of (β=0.48, p<0.01). Moreover, media factors (β=0.35, p<0.05) and social factors (β=0.30, p<0.05) also demonstrated a positive and significant relationship with the sustainable fashion design mindset. The results indicate the effective role of cultural, media, and social factors in strengthening students’ attitudes toward sustainable fashion design.