علوم و فناوری نساجی و پوشاک

علوم و فناوری نساجی و پوشاک

بررسی تاثیر نسبت ترکیب نانولیفچه‌های کیتوسان/نانوذرات اکسید روی بر خصوصیات نانوالیاف مرکب تولید شده

نوع مقاله : مقاله پژوهشی

نویسندگان
مرضیه رنجبر محمدی بناب 1
پریناز شکوری 2
1 1. بناب، دانشگاه بناب، دانشکده فنی و مهندسی، گروه مهندسی نساجی، کد پستی 5551761167
2 بناب، دانشگاه بناب، دانشکده فنی و مهندسی، گروه مهندسی نساجی، کد پستی 5551761167f Bonab
10.22034/jtst.2025.477859.1473
چکیده
Aim: This study investigated the potential application of a nanofibrous structure mimicking the natural extracellular matrix (ECM) of the body, composed of keratin/polyvinyl alcohol (K/PVA), polylactic acid (PLA), and chitosan nanofibrils/zinc oxide nanoparticles (ZnONPs/CHNF) (CSZ).

Methods: In this research, hybrid nanofibrous scaffolds were produced using K/PVA and PLA via the electrospinning method. K/PVA from one syringe and PLA from another were injected to produce hybrid nanofibers. Nanofibrillated chitosan/zinc oxide nanoparticles (ZnONPs/CHNF) (CSZ) at three different blend ratios (1:0, 2:1, and 1:2) were incorporated into the polymeric solutions containing K/PVA. The hydrophilicity of the samples was evaluated by measuring the contact angle, and the morphology of the produced scaffolds was examined using a scanning electron microscope (SEM). The effect of CSZ on morphology, hydrophilicity, and cell culture properties was then assessed.

Findings: The results demonstrated that the addition of ZnONPs to the CSZ solution led to a reduction in nanofiber diameter and an increase in the contact angle of the produced scaffolds. Extensive and suitable fibroblast cell growth was observed on the (2:1) PLA/CSZ-(2:1) K/PVA/CSZ sample. This sample, with a diameter of 352.50 ± 31 nm and a contact angle of 47 ± 3°, closely mimics the structure of the body's extracellular matrix (ECM). Its high surface-to-volume ratio enhances cell adhesion, proliferation, and growth, identifying it as the optimal sample.
کلیدواژه‌ها
کراتین
پلی وینیل الکل
پلی لاکتیک اسید
نانوفیبریل کیتوسان/نانوذرات اکسید روی
نانوالیاف

موضوعات

عنوان مقاله English

Investigation of the effect of the composition ratio of chitosan nanofibrils/zinc oxide nanoparticles on the properties of the produced composite nanofibers

نویسندگان English

Marziyeh Ranjbar-Mohammadi 1
Parinaz Shakoori 2
1 1. Textile group, Faculty of Engineering, University of Bonab, Postal Code 5551761167, Bonab, Iran
2 Textile group, Faculty of Engineering, University of Bonab, Postal Code 5551761167, Bonab, Iran
چکیده English

Aim: This study investigated the potential application of a nanofibrous structure mimicking the natural extracellular matrix (ECM) of the body, composed of keratin/polyvinyl alcohol (K/PVA), polylactic acid (PLA), and chitosan nanofibrils/zinc oxide nanoparticles (ZnONPs/CHNF) (CSZ).

Methods: In this research, hybrid nanofibrous scaffolds were produced using K/PVA and PLA via the electrospinning method. K/PVA from one syringe and PLA from another were injected to produce hybrid nanofibers. Nanofibrillated chitosan/zinc oxide nanoparticles (ZnONPs/CHNF) (CSZ) at three different blend ratios (1:0, 2:1, and 1:2) were incorporated into the polymeric solutions containing K/PVA. The hydrophilicity of the samples was evaluated by measuring the contact angle, and the morphology of the produced scaffolds was examined using a scanning electron microscope (SEM). The effect of CSZ on morphology, hydrophilicity, and cell culture properties was then assessed.

Findings: The results demonstrated that the addition of ZnONPs to the CSZ solution led to a reduction in nanofiber diameter and an increase in the contact angle of the produced scaffolds. Extensive and suitable fibroblast cell growth was observed on the (2:1) PLA/CSZ-(2:1) K/PVA/CSZ sample. This sample, with a diameter of 352.50 ± 31 nm and a contact angle of 47 ± 3°, closely mimics the structure of the body's extracellular matrix (ECM). Its high surface-to-volume ratio enhances cell adhesion, proliferation, and growth, identifying it as the optimal sample.

کلیدواژه‌ها English

Keratin
Poly vinyl alcohole
Polylactic acid
Nanofibers
Nanofibrillated chitosan/ZnO nanoparticles
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  • تاریخ دریافت 20 شهریور 1403
  • تاریخ بازنگری 19 دی 1403
  • تاریخ پذیرش 19 دی 1403