Investigation into the Effects of Nano-fibrous Wound Dressings on Wound Healing Process in Animal Models

Document Type : Review Article

Authors

1 textile engineering department,,isfahan university of technology

2 University of Social Welfare and Rehabilitation Sciences

Abstract

The skin is the largest organ of the body, with a total area of about 20 square feet. ... The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue and guards the underlying muscles, bones, ligaments and internal organ. WOUND IS an injury to living tissue caused by a cut, blow, or other impact, typically one in which the skin is cut or broken.
Novel wound dressings have practiced incessant and noteworthy variations as the earliest periods. The expansion begins with the usage of natural-materials to merely covering the wounds to the materials of the existing period that could be particularly manufactured to display numerous unexpected purposes. The modern bandage-materials constructed via bio-polymeric nano-fibers holding several active-compounds that are useful for the healing of wounds. With the correct selections of bio-polymers using for production of these nano-fibrous materials, they could improve the healing of wounds expressively compared with the conventional dressing materials, such as gauze. The novel wound dressings could be completed such that they have bio-active ingredients, for instance anti-microbial, anti-bacterial, and anti-inflammatory agents, which could be released to the wounds improving their healing.
This review offers an overview of various kinds of wounds, operational factors in wound healing and different forms of wound dressing materials with a superior highlighting to those manufactured of nanofibers.

Keywords